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Science Breakthroughs

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Science Breakthroughs — 2025
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Science Breakthroughs — 2025

Patient-specific in-vivo gene editing (medicine/genetics): The first known one-person personalized CRISPR base-editing treatment corrected a baby's CPS1 mutation.

2025-01-01 science-breakthroughs · 2025
Science Breakthroughs — 2024
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Science Breakthroughs — 2024

Twice-yearly lenacapavir for HIV prevention — Medicine and public health.

2024-01-01 science-breakthroughs · 2024
Science Breakthroughs — 2023
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Science Breakthroughs — 2023

First approved CRISPR therapy for sickle cell disease (medicine/genetics).

2023-01-01 science-breakthroughs · 2023
Science Breakthroughs — 2022
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Science Breakthroughs — 2022

James Webb Space Telescope first science images (astronomy): Webb's first full-color science images and spectra opened a new infrared view of the universe.

2022-01-01 science-breakthroughs · 2022
Science Breakthroughs — 2021
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Science Breakthroughs — 2021

WHO recommended the first malaria vaccine — selected as a historic public-health breakthrough.

2021-01-01 science-breakthroughs · 2021
Science Breakthroughs — 2020
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Science Breakthroughs — 2020

Black holes and the Galactic center: selected as the paired themes of the 2020 Nobel Prize in Physics, connecting theory with observations of the Milky Way's central compact object.

2020-01-01 science-breakthroughs · 2020
Science Breakthroughs — 2019
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Science Breakthroughs — 2019

First image of a black hole: selected as 2019's defining astronomy image, showing the M87 black-hole shadow as a glowing ring. Source: https://science.nasa.gov/resource/first-image-of-a-black-hole/

2019-01-01 science-breakthroughs · 2019
Science Breakthroughs — 2018
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Science Breakthroughs — 2018

Cancer immunotherapy / checkpoint inhibition: selected as the 2018 Nobel Prize in Physiology or Medicine and a major shift in cancer treatment.

2018-01-01 science-breakthroughs · 2018
Science Breakthroughs — 2017
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Science Breakthroughs — 2017

Colliding neutron stars / multimessenger astronomy: selected as Science's 2017 Breakthrough of the Year and a defining astronomy event.

2017-01-01 science-breakthroughs · 2017
Science Breakthroughs — 2016
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Science Breakthroughs — 2016

Zika public-health emergency and research response: selected as a major medicine/public-health story. Visualized with clean diagnostics, a mosquito icon, and fetal-health chart.

2016-01-01 science-breakthroughs · 2016
Science Breakthroughs — 2015
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Science Breakthroughs — 2015

CRISPR named Science's 2015 Breakthrough of the Year - selected as the leading genetics/biotech story. Visual: DNA and molecular scissors.

2015-01-01 science-breakthroughs · 2015
Science Breakthroughs — 2014
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Science Breakthroughs — 2014

Rosetta and Philae comet landing

2014-01-01 science-breakthroughs · 2014
Science Breakthroughs — 2013
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Science Breakthroughs — 2013

Cancer immunotherapy

2013-01-01 science-breakthroughs · 2013
Science Breakthroughs — 2012
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Science Breakthroughs — 2012

Higgs boson discovery

2012-01-01 science-breakthroughs · 2012
Science Breakthroughs — 2011
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Science Breakthroughs — 2011

HIV treatment as prevention

2011-01-01 science-breakthroughs · 2011
Science Breakthroughs — 2010
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Science Breakthroughs — 2010

First quantum machine, named Science's 2010 Breakthrough of the Year.

2010-01-01 science-breakthroughs · 2010
Science Breakthroughs — 2009
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Science Breakthroughs — 2009

LCROSS lunar water discovery

2009-01-01 science-breakthroughs · 2009
Science Breakthroughs — 2008
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Science Breakthroughs — 2008

Cellular reprogramming and induced pluripotent stem-cell advances.

2008-01-01 science-breakthroughs · 2008
Science Breakthroughs — 2007
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Science Breakthroughs — 2007

Human induced pluripotent stem cells: selected because 2007 reports extended reprogramming to human cells; depicted as skin cells transforming into glowing stem-cell colonies.

2007-01-01 science-breakthroughs · 2007
Science Breakthroughs — 2006
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Science Breakthroughs — 2006

Poincare Conjecture proof consensus. Selected because Science named it the 2006 Breakthrough of the Year.

2006-01-01 science-breakthroughs · 2006
Science Breakthroughs — 2005
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Science Breakthroughs — 2005

International HapMap Phase I: shown as DNA and SNP-marker maps.

2005-01-01 science-breakthroughs · 2005
Science Breakthroughs — 2004
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Science Breakthroughs — 2004

Spirit and Opportunity Mars rovers found evidence of past water. Selected because Science named the Mars rover discoveries its 2004 Breakthrough of the Year.

2004-01-01 science-breakthroughs · 2004
Science Breakthroughs — 2003
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Science Breakthroughs — 2003

Human Genome Project completion. Selected as the largest genetics milestone of the year. Source: https://www.genome.gov/about-genomics/educational-resources/fact-sheets/human-genome-project

2003-01-01 science-breakthroughs · 2003
Science Breakthroughs — 2002
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Science Breakthroughs — 2002

Solar neutrino problem resolved

2002-01-01 science-breakthroughs · 2002
Science Breakthroughs — 2001
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Science Breakthroughs — 2001

Draft human genome analysis published

2001-01-01 science-breakthroughs · 2001
Science Breakthroughs — 2000
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Science Breakthroughs — 2000

Draft human genome sequence: selected because the public consortium announced a working draft in June 2000; depicted with a glowing DNA helix and sequencing screens.

2000-01-01 science-breakthroughs · 2000